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BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski
BMCBI
2005
201views more  BMCBI 2005»
13 years 7 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
COMPLIFE
2006
Springer
13 years 11 months ago
Relational Subgroup Discovery for Descriptive Analysis of Microarray Data
Abstract. This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes different...
Igor Trajkovski, Filip Zelezný, Jakub Tolar...
BMCBI
2008
186views more  BMCBI 2008»
13 years 7 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
YANA - a software tool for analyzing flux modes, gene-expression and enzyme activities
Background: A number of algorithms for steady state analysis of metabolic networks have been developed over the years. Of these, Elementary Mode Analysis (EMA) has proven especial...
Roland Schwarz, Patrick Musch, Axel von Kamp, Bern...