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» Evolving Better Multiple Sequence Alignments
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BMCBI
2005
93views more  BMCBI 2005»
13 years 10 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
CEC
2007
IEEE
14 years 5 months ago
An evolutionary progressive multiple sequence alignment
Abstract This paper presents a new evolutionary method, namely, a Two Phase evolutionary algorithm for multiple sequence alignments. This method is composed of different types of e...
Farhana Naznin, Morikazu Nakamura, Takeo Okazaki, ...
BMCBI
2005
134views more  BMCBI 2005»
13 years 10 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
14 years 2 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
BMCBI
2008
78views more  BMCBI 2008»
13 years 11 months ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...