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BMCBI
2006
120views more  BMCBI 2006»
13 years 8 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
180views more  BMCBI 2006»
13 years 8 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
97views more  BMCBI 2006»
13 years 8 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
107views more  BMCBI 2006»
13 years 8 months ago
CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
Jussi Paananen, Markus Storvik, Garry Wong
DM
2006
128views more  DM 2006»
13 years 8 months ago
Non-trivial t-designs without repeated blocks exist for all t
A computer package is being developed at Bayreuth for the generation and investigation of discrete structures. The package is a C and C++ class library of powerful algorithms endow...
Luc Teirlinck