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BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
BMCBI
2005
107views more  BMCBI 2005»
13 years 7 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
BMCBI
2005
125views more  BMCBI 2005»
13 years 7 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Modelling the correlation between the activities of adjacent genes in drosophila
Background: Correlation between the expression levels of genes which are located close to each other on the genome has been found in various organisms, including yeast, drosophila...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
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