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BMCBI
2011
13 years 1 months ago
2011
Background: The secondary structure of RNA molecules is intimately related to their function and often more conserved than the sequence. Hence, the important task of searching dat...
BMCBI
2011
13 years 1 months ago
2011
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
BMCBI
2011
13 years 1 months ago
2011
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
BMCBI
2011
13 years 1 months ago
2011
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
BMCBI
2011
13 years 1 months ago
2011
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...