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BMCBI
2010
13 years 10 months ago
2010
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
BMCBI
2008
13 years 10 months ago
2008
Background: Simple Sequence Repeat (SSR) or microsatellite markers are valuable for genetic research. Experimental methods to develop SSR markers are laborious, time consuming and...
BMCBI
2008
13 years 10 months ago
2008
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
BMCBI
2008
13 years 10 months ago
2008
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
BMCBI
2008
13 years 10 months ago
2008
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...