The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
— This paper presents an approach to the multiple sequence alignment (MSA) problem by applying genetic algorithms with a reserve selection mechanism. MSA is one of the most funda...
Yang Chen, Jinglu Hu, Kotaro Hirasawa, Songnian Yu
Huber's M-estimation technique is applied to a block-angular regression problem, which may arise from some applications. A recursive, modified Newton approach to computing th...
In this paper, we propose to apply sparse canonical correlation analysis (sparse CCA) to an important genome-wide association study problem, eQTL mapping. Existing sparse CCA mode...
Abstract. This paper describes a novel approach to recovering a parametric deformation that optimally registers one image to another. The method proceeds by constructing a global c...