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BMCBI
2010
133views more  BMCBI 2010»
13 years 9 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2010
86views more  BMCBI 2010»
13 years 9 months ago
The oligodeoxynucleotide sequences corresponding to never-expressed peptide motifs are mainly located in the non-coding strand
Background: We study the usage of specific peptide platforms in protein composition. Using the pentapeptide as a unit of length, we find that in the universal proteome many pentap...
Giovanni Capone, Giuseppe Novello, Candida Fasano,...
BMCBI
2008
103views more  BMCBI 2008»
13 years 9 months ago
The VirusBanker database uses a Java program to allow flexible searching through Bunyaviridae sequences
Background: Viruses of the Bunyaviridae have segmented negative-stranded RNA genomes and several of them cause significant disease. Many partial sequences have been obtained from ...
Mathieu Fourment, Mark J. Gibbs
BMCBI
2008
211views more  BMCBI 2008»
13 years 9 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
CAD
2008
Springer
13 years 9 months ago
Tracking product specification dependencies in collaborative design for conflict management
The main difficulty associated with a collaborative design process is understanding the product data exchanged during design. Efficient and effective coordination of design activi...
Mohamed-Zied Ouertani, Lilia Gzara Yesilbas