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    GPB
    2010
    231views Solid Modeling» more  GPB 2010»
    Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
    13 years 6 months ago
    Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
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    The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
    Ferran Reverter, Esteban Vegas, Pedro Sánch...
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    BMCBI
    2008
    142views more  BMCBI 2008»
    Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
    13 years 9 months ago
    Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
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    Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
    Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
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    BMCBI
    2004
    139views more  BMCBI 2004»
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
    13 years 8 months ago
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
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    Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
    Jeffrey P. Townsend
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    BMCBI
    2008
    115views more  BMCBI 2008»
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    13 years 9 months ago
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
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    Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
    Sudhakar Jonnalagadda, Rajagopalan Srinivasan
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    BMCBI
    2005
    133views more  BMCBI 2005»
    Ab initio identification of putative human transcription factor binding sites by comparative genomics
    13 years 8 months ago
    Ab initio identification of putative human transcription factor binding sites by comparative genomics
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    Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
    Davide Corà, Carl Herrmann, Christoph Diete...
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