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BMCBI
2004
132views more  BMCBI 2004»
13 years 7 months ago
Two-stage normalization using background intensities in cDNA microarray data
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
Dankyu Yoon, Sung-Gon Yi, Ju-Han Kim, Taesung Park
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
COMPLIFE
2005
Springer
14 years 1 months ago
Robust Perron Cluster Analysis for Various Applications in Computational Life Science
In the present paper we explain the basic ideas of Robust Perron Cluster Analysis (PCCA+) and exemplify the different application areas of this new and powerful method. Recently, ...
Marcus Weber, Susanna Kube
GECCO
2005
Springer
146views Optimization» more  GECCO 2005»
14 years 1 months ago
An empirical study of the robustness of two module clustering fitness functions
Two of the attractions of search-based software engineering (SBSE) derive from the nature of the fitness functions used to guide the search. These have proved to be highly robust...
Mark Harman, Stephen Swift, Kiarash Mahdavi
CDC
2009
IEEE
179views Control Systems» more  CDC 2009»
14 years 8 days ago
Bayesian network approach to understand regulation of biological processes in cyanobacteria
— Bayesian networks have extensively been used in numerous fields including artificial intelligence, decision theory and control. Its ability to utilize noisy and missing data ...
Thanura R. Elvitigala, Abhay K. Singh, Himadri B. ...