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BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
14 years 3 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
BMCBI
2004
108views more  BMCBI 2004»
13 years 10 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
CSB
2004
IEEE
136views Bioinformatics» more  CSB 2004»
14 years 1 months ago
Minimum Entropy Clustering and Applications to Gene Expression Analysis
Clustering is a common methodology for analyzing the gene expression data. In this paper, we present a new clustering algorithm from an information-theoretic point of view. First,...
Haifeng Li, Keshu Zhang, Tao Jiang
BMCBI
2004
90views more  BMCBI 2004»
13 years 10 months ago
Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Mic...
ISNN
2005
Springer
14 years 3 months ago
An Information Criterion for Informative Gene Selection
It is important in bioinformatics research and applications to select or discover informative genes of a tumor from microarray data. However, most of the existing methods are based...
Fei Ge, Jinwen Ma