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» Extracting active pathways from gene expression data
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APBC
2003
120views Bioinformatics» more  APBC 2003»
13 years 10 months ago
From Informatics to Bioinformatics
Informatics has helped in launching molecular biology into the genomic era. It appears certain that informatics will continue to be a major factor in the success of molecular biol...
Vladimir B. Bajic, Vladimir Brusic, Jinyan Li, See...
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 9 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
ECCB
2003
IEEE
14 years 2 months ago
Gene networks inference using dynamic Bayesian networks
This article deals with the identification of gene regulatory networks from experimental data using a statistical machine learning approach. A stochastic model of gene interactio...
Bruno-Edouard Perrin, Liva Ralaivola, Aurél...
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
13 years 8 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
JIB
2007
119views more  JIB 2007»
13 years 8 months ago
VINEdb: a data warehouse for integration and interactive exploration of life science data
Control of cell proliferation, differentiation, activation and cell removal is crucial for the development and existence of multi-cellular organisms. Apoptosis, or programmed cell...
Sridhar Hariharaputran, Thoralf Töpel, Bj&oum...