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» Extracting active pathways from gene expression data
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BMCBI
2010
99views more  BMCBI 2010»
13 years 7 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BMCBI
2005
163views more  BMCBI 2005»
13 years 7 months ago
Alkahest NuclearBLAST: a user-friendly BLAST management and analysis system
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
BMCBI
2010
155views more  BMCBI 2010»
13 years 7 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
PKDD
2005
Springer
123views Data Mining» more  PKDD 2005»
14 years 1 months ago
A Multi-metric Index for Euclidean and Periodic Matching
In many classification and data-mining applications the user does not know a priori which distance measure is the most appropriate for the task at hand without examining the produ...
Michail Vlachos, Zografoula Vagena, Vittorio Caste...