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» Extracting and Explaining Biological Knowledge in Microarray...
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BMCBI
2010
170views more  BMCBI 2010»
13 years 11 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
NLDB
2005
Springer
14 years 4 months ago
Combining Biological Databases and Text Mining to Support New Bioinformatics Applications
Abstract. A large amount of biological knowledge today is only available from full-text research papers. Since neither manual database curators nor users can keep up with the rapid...
René Witte, Christopher J. O. Baker
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
13 years 11 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
ISMB
1993
14 years 4 days ago
Prediction of Primate Splice Junction Gene Sequences with a Cooperative Knowledge Acquisition System
Wepropose a cooperative conceptual modelling environment in which two agents interact : the machineand the humanexpert. Theformer is able to extract knowledge from data using a sy...
Engelbert Mephu Nguifo, Jean Sallantin
BMCBI
2008
83views more  BMCBI 2008»
13 years 11 months ago
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
Atsushi Niida, Andrew D. Smith, Seiya Imoto, Shuic...