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BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
BMCBI
2005
103views more  BMCBI 2005»
13 years 8 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
KDD
2012
ACM
242views Data Mining» more  KDD 2012»
11 years 11 months ago
Query-driven discovery of semantically similar substructures in heterogeneous networks
Heterogeneous information networks that contain multiple types of objects and links are ubiquitous in the real world, such as bibliographic networks, cyber-physical networks, and ...
Xiao Yu, Yizhou Sun, Peixiang Zhao, Jiawei Han
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
14 years 2 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
ALMOB
2007
111views more  ALMOB 2007»
13 years 8 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...