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CORR
2010
Springer
122views Education» more  CORR 2010»
15 years 4 months ago
Facility Location with Client Latencies: Linear-Programming based Techniques for Minimum-Latency Problems
We introduce a problem that is a common generalization of the uncapacitated facility location (UFL) and minimum latency (ML) problems, where facilities not only need to be opened ...
Deeparnab Chakrabarty, Chaitanya Swamy
BMCBI
2006
138views more  BMCBI 2006»
15 years 4 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2006
123views more  BMCBI 2006»
15 years 4 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger
BMCBI
2006
123views more  BMCBI 2006»
15 years 4 months ago
Permutation test for periodicity in short time series data
Background: Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretica...
Andrey A. Ptitsyn, Sanjin Zvonic, Jeffrey M. Gimbl...
BMCBI
2006
127views more  BMCBI 2006»
15 years 4 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...