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BMCBI
2006
78views more  BMCBI 2006»
13 years 6 months ago
Modelling study of dimerization in mammalian defensins
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
Anita Suresh, Chandra Verma
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
Cell_motility: a cross-platform, open source application for the study of cell motion paths
Background: Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in...
Lennart Martens, Geert Monsieur, Christophe Ampe, ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2006
113views more  BMCBI 2006»
13 years 6 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
CORR
2006
Springer
146views Education» more  CORR 2006»
13 years 6 months ago
Approximation Algorithms for Multi-Criteria Traveling Salesman Problems
In multi-criteria optimization, several objective functions are to be optimized. Since the different objective functions are usually in conflict with each other, one cannot conside...
Bodo Manthey, L. Shankar Ram