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ENGL
2008
78views more  ENGL 2008»
13 years 10 months ago
Threshold for Positional Weight Matrix
In biological sequence research, the positional weight matrix (PWM) is often used to search for putative transcription factor binding sites. A set of experimentally verified oligon...
Yunlian Pan, Sieu Phan
KDD
2008
ACM
115views Data Mining» more  KDD 2008»
14 years 10 months ago
SPIRAL: efficient and exact model identification for hidden Markov models
Hidden Markov models (HMMs) have received considerable attention in various communities (e.g, speech recognition, neurology and bioinformatic) since many applications that use HMM...
Yasuhiro Fujiwara, Yasushi Sakurai, Masashi Yamamu...
BMCBI
2010
155views more  BMCBI 2010»
13 years 7 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2010
101views more  BMCBI 2010»
13 years 10 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
GCB
1998
Springer
78views Biometrics» more  GCB 1998»
14 years 2 months ago
Computational approaches to identify Leucine Zippers
The leucine zipper is a dimerization domain occurring mostly in regulatory and thus in many oncogenic proteins. The leucine repeat in the sequence has been traditionally used for ...
Erich Bornberg-Bauer