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BMCBI
2011
12 years 11 months ago
Conotoxin Protein Classification Using Free Scores of Words and Support Vector Machines
Background: Conotoxin has been proven to be effective in drug design and could be used to treat various disorders such as schizophrenia, neuromuscular disorders and chronic pain. ...
Nazar Zaki, Stefan Wolfsheimer, Grégory Nue...
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
WABI
2001
Springer
142views Bioinformatics» more  WABI 2001»
14 years 2 days ago
Pattern Matching and Pattern Discovery Algorithms for Protein Topologies
We describe algorithms for pattern matching and pattern learning in TOPS diagrams (formal descriptions of protein topologies). These problems can be reduced to checking for subgrap...
Juris Viksna, David Gilbert
BMCBI
2006
102views more  BMCBI 2006»
13 years 7 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
CAIP
2009
Springer
155views Image Analysis» more  CAIP 2009»
14 years 2 months ago
Algorithms for the Sample Mean of Graphs
Measures of central tendency for graphs are important for protoype construction, frequent substructure mining, and multiple alignment of protein structures. This contribution propo...
Brijnesh J. Jain, Klaus Obermayer