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CSB
2003
IEEE
14 years 1 months ago
Fast and Sensitive Probe Selection for DNA Chips Using Jumps in Matching Statistics
The design of large scale DNA microarrays is a challenging problem. So far, probe selection algorithms must trade the ability to cope with large scale problems for a loss of accur...
Sven Rahmann
BMCBI
2005
132views more  BMCBI 2005»
13 years 8 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2010
134views more  BMCBI 2010»
13 years 8 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
14 years 3 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
NIPS
2003
13 years 10 months ago
Fast Feature Selection from Microarray Expression Data via Multiplicative Large Margin Algorithms
New feature selection algorithms for linear threshold functions are described which combine backward elimination with an adaptive regularization method. This makes them particular...
Claudio Gentile