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JCB
2002
108views more  JCB 2002»
13 years 8 months ago
Fast and Accurate Phylogeny Reconstruction Algorithms Based on the Minimum-Evolution Principle
This paper investigates the standard ordinary least-squares version 24 and the balanced version 20 of the minimum evolution principle. For the standard version, we provide a greedy...
Richard Desper, Olivier Gascuel
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
BMCBI
2008
220views more  BMCBI 2008»
13 years 8 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
SSDBM
2003
IEEE
141views Database» more  SSDBM 2003»
14 years 1 months ago
The ed-tree: An Index for Large DNA Sequence Databases
The growing interest in genomic research has caused an explosive growth in the size of DNA databases making it increasely challenging to perform searches on them. In this paper, w...
Zhenqiang Tan, Xia Cao, Beng Chin Ooi, Anthony K. ...
BMCBI
2008
133views more  BMCBI 2008»
13 years 8 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...