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BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
JMIV
2006
185views more  JMIV 2006»
13 years 7 months ago
Intrinsic Statistics on Riemannian Manifolds: Basic Tools for Geometric Measurements
In medical image analysis and high level computer vision, there is an intensive use of geometric features like orientations, lines, and geometric transformations ranging from simp...
Xavier Pennec
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
JCC
2011
154views more  JCC 2011»
12 years 10 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
LCTRTS
2010
Springer
14 years 2 months ago
Design exploration and automatic generation of MPSoC platform TLMs from Kahn Process Network applications
With increasingly more complex Multi-Processor Systems on Chip (MPSoC) and shortening time-to- market projections, Transaction Level Modeling and Platform Aware Design are seen as...
Ines Viskic, Lochi Lo Chi Yu Lo, Daniel Gajski