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BMCBI
2005
62views more  BMCBI 2005»
13 years 7 months ago
Differences in codon bias cannot explain differences in translational power among microbes
Background: Translational power is the cellular rate of protein synthesis normalized to the biomass invested in translational machinery. Published data suggest a previously unreco...
Les Dethlefsen, Thomas M. Schmidt
GPEM
2007
119views more  GPEM 2007»
13 years 7 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
EMAAS: An extensible grid-based Rich Internet Application for microarray data analysis and management
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
Geraint Barton, J. C. Abbott, Norie Chiba, D. W. H...