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EJASP
2010
132views more  EJASP 2010»
13 years 2 months ago
Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
HYBRID
2007
Springer
14 years 1 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
HISB
2011
99views more  HISB 2011»
12 years 7 months ago
Quantitative Modeling the Saccharomyces cerevisiae FLR1 Regulatory Network Using an S-System Formalism
—We address the problem of finding a mathematical model for the genetic network regulating the stress response of the yeast Saccharomyces cerevisiae to the fungicide mancozeb. A...
Dulce Calçada, Susana Vinga, Ana T. Freitas...
ALIFE
2008
13 years 7 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
BMCBI
2008
154views more  BMCBI 2008»
13 years 7 months ago
GeNESiS: gene network evolution simulation software
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
Anton Kratz, Masaru Tomita, Arun Krishnan