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RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
AVI
2006
13 years 8 months ago
Line graph explorer: scalable display of line graphs using Focus+Context
Scientific measurements are often depicted as line graphs. Stateof-the-art high throughput systems in life sciences, telemetry and electronics measurement rapidly generate hundred...
Robert Kincaid, Heidi Lam
APVIS
2009
13 years 8 months ago
Toward effective insight management in visual analytics systems
Although significant progress has been made toward effective insight discovery in visual sense making approaches, there is a lack of effective and efficient approaches to manage t...
Yang Chen, Jing Yang, William Ribarsky
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi