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BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BIRD
2008
Springer
162views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Suffix Tree Characterization of Maximal Motifs in Biological Sequences
Finding motifs in biological sequences is one of the most intriguing problems for string algorithms designers due to, on the one hand, the numerous applications of this problem in...
Maria Federico, Nadia Pisanti