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» Finding Dynamic Modules of Biological Regulatory Networks
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AB
2008
Springer
14 years 2 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 8 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Meta Analysis of Microarray Data Using Gene Regulation Pathways
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a ...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 9 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
BMCBI
2006
202views more  BMCBI 2006»
13 years 8 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau