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» Finding Dynamic Modules of Biological Regulatory Networks
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TSP
2008
134views more  TSP 2008»
13 years 8 months ago
Effect of Function Perturbation on the Steady-State Distribution of Genetic Regulatory Networks: Optimal Structural Intervention
Abstract--The dynamics of a rule-based gene regulatory network are determined by the regulatory functions in conjunction with whatever probability distributions are involved in net...
Xiaoning Qian, Edward R. Dougherty
BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
HYBRID
2007
Springer
14 years 2 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss
BIOCOMP
2010
13 years 6 months ago
Robust Stability Analysis and Design Under Consideration of Multiple Feedback Loops in the Tryptophan Regulatory Network of E. c
The tryptophan operon of E. coli represents an important regulatory unit consisting of multiple feedback loops. The role of these loops is crucial to understand the dynamics of tr...
Anke Meyer-Bäse, Fabian J. Theis
CIBCB
2005
IEEE
14 years 2 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...