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» Finding Motifs with Gaps
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BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
ICDE
2010
IEEE
750views Database» more  ICDE 2010»
14 years 29 days ago
Efficient and accurate discovery of patterns in sequence datasets
Existing sequence mining algorithms mostly focus on mining for subsequences. However, a large class of applications, such as biological DNA and protein motif mining, require effici...
Avrilia Floratou, Sandeep Tata, Jignesh M. Patel
COCOON
2008
Springer
13 years 10 months ago
Quasi-bicliques: Complexity and Binding Pairs
Abstract. Protein-protein interactions (PPIs) are one of the most important mechanisms in cellular processes. To model protein interaction sites, recent studies have suggested to f...
Xiaowen Liu, Jinyan Li, Lusheng Wang
BMCBI
2006
87views more  BMCBI 2006»
13 years 8 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...