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» Finding Motifs with Gaps
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CIBCB
2007
IEEE
14 years 3 months ago
Motifs and Modules in Fractured Functional Yeast Networks
The integration of diverse data sets into probabilistic functional networks is an active and important area of research in systems biology. In this paper we fracture a previously p...
Jennifer Hallinan, Anil Wipat
DEXAW
2009
IEEE
135views Database» more  DEXAW 2009»
14 years 15 days ago
Motif Discovery in Brain Networks of Patients with Somatoform Pain Disorder
Idiopathic chronic pain disorders constitude a large, clinically important health care problem that urgently needs deeper pathophysiological insight. The understanding which brain ...
Annahita Oswald, Bianca Wackersreuther
RECOMB
2005
Springer
14 years 9 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
ICMLA
2008
13 years 10 months ago
Ensemble Machine Methods for DNA Binding
We introduce three ensemble machine learning methods for analysis of biological DNA binding by transcription factors (TFs). The goal is to identify both TF target genes and their ...
Yue Fan, Mark A. Kon, Charles DeLisi
NIPS
2004
13 years 10 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...