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BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
BMCBI
2004
117views more  BMCBI 2004»
13 years 8 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
SIGMOD
2008
ACM
144views Database» more  SIGMOD 2008»
14 years 8 months ago
Mining significant graph patterns by leap search
With ever-increasing amounts of graph data from disparate sources, there has been a strong need for exploiting significant graph patterns with user-specified objective functions. ...
Xifeng Yan, Hong Cheng, Jiawei Han, Philip S. Yu
BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
BMCBI
2008
149views more  BMCBI 2008»
13 years 8 months ago
Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...