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» Finding Similar Patterns in Microarray Data
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ITA
2006
167views Communications» more  ITA 2006»
13 years 9 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino
BMCBI
2004
146views more  BMCBI 2004»
13 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2010
115views more  BMCBI 2010»
13 years 10 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
132views more  BMCBI 2010»
13 years 10 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BIBM
2008
IEEE
212views Bioinformatics» more  BIBM 2008»
14 years 4 months ago
Analysis of Multiplex Gene Expression Maps Obtained by Voxelation
Background: Gene expression signatures in the mammalian brain hold the key to understanding neural development and neurological disease. Researchers have previously used voxelatio...
Li An, Hongbo Xie, Mark H. Chin, Zoran Obradovic, ...