As a culture, object-orientation encourages programmers to create objects, both short- and long-lived, without concern for cost. Excessive object creation and initialization can ca...
Background: One of the strategies for protein function annotation is to search particular structural motifs that are known to be shared by proteins with a given function. Results:...
This paper describes transformation techniques for out-of-core programs (i.e., those that deal with very large quantities of data) based on exploiting locality using a combination...
Mahmut T. Kandemir, Alok N. Choudhary, J. Ramanuja...
The growing speed gap between memory and processor makes an efficient use of the cache ever more important to reach high performance. One of the most important ways to improve cac...
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....