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BMCBI
2008
139views more  BMCBI 2008»
13 years 10 months ago
The C1C2: A framework for simultaneous model selection and assessment
Background: There has been recent concern regarding the inability of predictive modeling approaches to generalize to new data. Some of the problems can be attributed to improper m...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2008
75views more  BMCBI 2008»
13 years 10 months ago
Re-searcher: a system for recurrent detection of homologous protein sequences
Background: Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence s...
Valdemaras Repsys, Mindaugas Margelevicius, Ceslov...
BMCBI
2008
98views more  BMCBI 2008»
13 years 10 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
BMCBI
2008
171views more  BMCBI 2008»
13 years 10 months ago
Comparative analysis of five protein-protein interaction corpora
Background: Growing interest in the application of natural language processing methods to biomedical text has led to an increasing number of corpora and methods targeting protein-...
Sampo Pyysalo, Antti Airola, Juho Heimonen, Jari B...
BMCBI
2008
125views more  BMCBI 2008»
13 years 10 months ago
Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
Background: The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better unders...
Lesheng Kong, Shoba Ranganathan