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BMCBI
2008
67views more  BMCBI 2008»
13 years 11 months ago
Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal p
Background: Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated acr...
Khar Heng Choo, Joo Chuan Tong, Shoba Ranganathan
ISMB
1998
14 years 6 days ago
Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
Henrik Nielsen, Anders Krogh