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BMCBI
2008
160views more  BMCBI 2008»
15 years 4 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
BMCBI
2008
159views more  BMCBI 2008»
15 years 4 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2008
91views more  BMCBI 2008»
15 years 4 months ago
Presenting and exploring biological pathways with PathVisio
nd: Biological pathways are a useful abstraction of biological concepts, and software tools to deal with pathway diagrams can help biological research. PathVisio is a new visualiz...
Martijn P. van Iersel, Thomas Kelder, Alexander R....
CORR
2010
Springer
119views Education» more  CORR 2010»
15 years 4 months ago
Report on the XBase Project
This project addressed the conceptual fundamentals of data storage, investigating techniques for provision of highly generic storage facilities that can be tailored to produce var...
Evangelos Zirintsis, Graham N. C. Kirby, Alan Dear...