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BMCBI
2008
135views more  BMCBI 2008»
15 years 4 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
CORR
2010
Springer
200views Education» more  CORR 2010»
15 years 4 months ago
Unified Compression-Based Acceleration of Edit-Distance Computation
The edit distance problem is a classical fundamental problem in computer science in general, and in combinatorial pattern matching in particular. The standard dynamic programming s...
Danny Hermelin, Gad M. Landau, Shir Landau, Oren W...
BMCBI
2006
165views more  BMCBI 2006»
15 years 4 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...
BMCBI
2006
143views more  BMCBI 2006»
15 years 4 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
CORR
2006
Springer
153views Education» more  CORR 2006»
15 years 4 months ago
Genetic Programming, Validation Sets, and Parsimony Pressure
Fitness functions based on test cases are very common in Genetic Programming (GP). This process can be assimilated to a learning task, with the inference of models from a limited n...
Christian Gagné, Marc Schoenauer, Marc Pari...
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