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BMCBI
2005
127views more  BMCBI 2005»
13 years 10 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2005
116views more  BMCBI 2005»
13 years 10 months ago
SuperLigands - a database of ligand structures derived from the Protein Data Bank
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
Elke Michalsky, Mathias Dunkel, Andrean Goede, Rob...
BMCBI
2005
196views more  BMCBI 2005»
13 years 10 months ago
Chemistry in Bioinformatics
Chemical information is now seen as critical for most areas of life sciences. But unlike Bioinformatics, where data is Openly available and freely re-usable, most chemical informa...
Peter Murray-Rust, John B. O. Mitchell, Henry S. R...
BMCBI
2005
118views more  BMCBI 2005»
13 years 10 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2005
98views more  BMCBI 2005»
13 years 10 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
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