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BMCBI
2005
103views more  BMCBI 2005»
13 years 9 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate
BMCBI
2005
137views more  BMCBI 2005»
13 years 9 months ago
A standard curve based method for relative real time PCR data processing
Background: Currently real time PCR is the most precise method by which to measure gene expression. The method generates a large amount of raw numerical data and processing may no...
Alexey Larionov, Andreas Krause, William Miller
BMCBI
2005
107views more  BMCBI 2005»
13 years 9 months ago
Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Jun Lu, John K. Tomfohr, Thomas B. Kepler
BMCBI
2005
167views more  BMCBI 2005»
13 years 9 months ago
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
Background: The extensive use of DNA microarray technology in the characterization of the cell transcriptome is leading to an ever increasing amount of microarray data from cancer...
Patrick Warnat, Roland Eils, Benedikt Brors
BMCBI
2005
121views more  BMCBI 2005»
13 years 9 months ago
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) ma
Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...