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» Framework for a Protein Ontology
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BIOINFORMATICS
2006
95views more  BIOINFORMATICS 2006»
13 years 8 months ago
Family specific rates of protein evolution
: Amino acid changing mutations in proteins are contstrained by purifying selection and accumulate at different rates. We estimate evolutionary rates on multiple alignments of euka...
Hannes Luz, Martin Vingron
BMCBI
2008
146views more  BMCBI 2008»
13 years 9 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
BMCBI
2004
229views more  BMCBI 2004»
13 years 8 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
DILS
2007
Springer
14 years 2 months ago
Instance-Based Matching of Large Life Science Ontologies
Ontologies are heavily used in life sciences so that there is increasing value to match different ontologies in order to determine related conceptual categories. We propose a simpl...
Toralf Kirsten, Andreas Thor, Erhard Rahm
BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
13 years 9 months ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...