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BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
CMSB
2009
Springer
14 years 2 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
BIOCOMP
2008
13 years 9 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
WWW
2009
ACM
14 years 8 months ago
Extracting community structure through relational hypergraphs
Social media websites promote diverse user interaction on media objects as well as user actions with respect to other users. The goal of this work is to discover community structu...
Yu-Ru Lin, Jimeng Sun, Paul Castro, Ravi B. Konuru...
PPSN
2000
Springer
13 years 11 months ago
Optimizing through Co-evolutionary Avalanches
Abstract. We explore a new general-purpose heuristic for nding highquality solutions to hard optimization problems. The method, called extremal optimization, is inspired by self-or...
Stefan Boettcher, Allon G. Percus, Michelangelo Gr...