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BMCBI
2010
117views more  BMCBI 2010»
13 years 9 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
ASSETS
2006
ACM
14 years 3 months ago
American sign language recognition in game development for deaf children
CopyCat is an American Sign Language (ASL) game, which uses gesture recognition technology to help young deaf children practice ASL skills. We describe a brief history of the game...
Helene Brashear, Valerie L. Henderson, Kwang-Hyun ...
CORR
2010
Springer
174views Education» more  CORR 2010»
13 years 9 months ago
Hybrid Numerical Solution of the Chemical Master Equation
We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the ...
Thomas A. Henzinger, Maria Mateescu, Linar Mikeev,...
STOC
2012
ACM
221views Algorithms» more  STOC 2012»
11 years 11 months ago
From query complexity to computational complexity
We consider submodular optimization problems, and provide a general way of translating oracle inapproximability results arising from the symmetry gap technique to computational co...
Shahar Dobzinski, Jan Vondrák
SARA
2009
Springer
14 years 3 months ago
Some Interval Approximation Techniques for MINLP
MINLP problems are hard constrained optimization problems, with nonlinear constraints and mixed discrete continuous variables. They can be solved using a Branch-and-Bound scheme c...
Nicolas Berger, Laurent Granvilliers