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BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
196
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BMCBI
2010
190views more  BMCBI 2010»
15 years 6 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2010
86views more  BMCBI 2010»
15 years 6 months ago
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Evgeniy V. Petrotchenko, Christoph H. Borchers
BMCBI
2010
137views more  BMCBI 2010»
15 years 6 months ago
Biana: a software framework for compiling biological interactions and analyzing networks
Background: The analysis and usage of biological data is hindered by the spread of information across multiple repositories and the difficulties posed by different nomenclature sy...
Javier Garcia-Garcia, Emre Guney, Ramon Aragues, J...
BMCBI
2010
172views more  BMCBI 2010»
15 years 6 months ago
Accessing the SEED genome databases via Web services API: tools for programmers
Background: The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems ...
Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Ol...
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