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BMCBI
2008
13 years 10 months ago
2008
Background: Pancreatic cancer is the fourth leading cause of cancer death in the United States. Consequently, identification of clinically relevant biomarkers for the early detect...
BMCBI
2008
13 years 10 months ago
2008
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
BMCBI
2008
13 years 10 months ago
2008
Background: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides...
BMCBI
2008
13 years 10 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2008
13 years 10 months ago
2008
Background: Despite considerable efforts within the microarray community for standardising data format, content and description, microarray technologies present major challenges i...