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BMCBI
2010
13 years 9 months ago
2010
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
BMCBI
2010
13 years 9 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
BMCBI
2010
13 years 9 months ago
2010
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
BMCBI
2010
13 years 9 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2010
13 years 9 months ago
2010
Background: In the current era of scientific research, efficient communication of information is paramount. As such, the nature of scholarly and scientific communication is changi...