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BMCBI
2006
141views more  BMCBI 2006»
13 years 8 months ago
The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
Background: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of...
Alexander García Castro, Philippe Rocca-Ser...
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen
BMCBI
2006
124views more  BMCBI 2006»
13 years 8 months ago
HybGFS: a hybrid method for genome-fingerprint scanning
Background: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. H...
Kosaku Shinoda, Nozomu Yachie, Takeshi Masuda, Nao...
BMCBI
2006
117views more  BMCBI 2006»
13 years 8 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
Taking U out, with two nucleases?
Background: REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are ...
I. Saira Mian, Elizabeth A. Worthey, Reza Salavati