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BIBE
2006
IEEE
137views Bioinformatics» more  BIBE 2006»
14 years 4 months ago
Leveraging Chemical Background Knowledge for the Prediction of Growth Inhibition
We show how chemical background knowledge can be used to improve the prediction performance in structureactivitity relationships (SARs) for non-congeneric compounds. The goal of t...
Lothar Richter, Stefan Hechtl, Stefan Kramer
BIBE
2006
IEEE
160views Bioinformatics» more  BIBE 2006»
14 years 4 months ago
Methods for Random Modularization of Biological Networks
— Biological networks are formalized summaries of our knowledge about interactions among biological system components, like genes, proteins, or metabolites. From their global top...
Zachary M. Saul, Vladimir Filkov
IPPS
2006
IEEE
14 years 4 months ago
Multiple sequence alignment by quantum genetic algorithm
In this paper we describe a new approach for the well known problem in bioinformatics: Multiple Sequence Alignment (MSA). MSA is fundamental task as it represents an essential pla...
L. Abdesslem, M. Soham, B. Mohamed
BIBE
2005
IEEE
107views Bioinformatics» more  BIBE 2005»
14 years 3 months ago
DSIM: A Distance-Based Indexing Method for Genomic Sequences
In this paper, we propose a Distance-based Sequence Indexing Method (DSIM) for indexing and searching genome databases. Borrowing the idea of video compression, we compress the ge...
Xia Cao, Beng Chin Ooi, HweeHwa Pang, Kian-Lee Tan...
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
14 years 3 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh