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ISBRA
2010
Springer
14 years 1 months ago
A Novel Approach for Compressing Phylogenetic Trees
Abstract. Phylogenetic trees are tree structures that depict relationships between organisms. Popular analysis techniques often produce large collections of candidate trees, which ...
Suzanne Matthews, Seung-Jin Sul, Tiffani L. Willia...
BIRD
2008
Springer
14 years 5 days ago
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from...
Ulrike Mückstein, Hakim Tafer, Stephan H. F. ...
BIRD
2008
Springer
158views Bioinformatics» more  BIRD 2008»
14 years 5 days ago
A Computational Method for Reconstructing Gapless Metabolic Networks
Abstract. We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of b...
Esa Pitkänen, Ari Rantanen, Juho Rousu, Esko ...
BIBE
2005
IEEE
14 years 4 days ago
A Multi-Level Approach to SCOP Fold Recognition
The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
CSB
2005
IEEE
128views Bioinformatics» more  CSB 2005»
14 years 3 days ago
Application of a Generalized MWC Model for the Mathematical Simulation of Metabolic Pathways Regulated by Allosteric Enzymes
In our effort to elucidate the systems biology of the model organism, Escherichia coli, we have developed a mathematical model that simulates the allosteric regulation for threoni...
Tarek S. Najdi, Chin-Rang Yang, Bruce E. Shapiro, ...