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BIBM
2009
IEEE
190views Bioinformatics» more  BIBM 2009»
13 years 8 months ago
A Fast, Semi-automatic Brain Structure Segmentation Algorithm for Magnetic Resonance Imaging
Abstract--Medical image segmentation has become an essential technique in clinical and research-oriented applications. Because manual segmentation methods are tedious, and fully au...
Kevin Karsch, Qing He, Ye Duan
IMSCCS
2007
IEEE
14 years 4 months ago
Evolutionary Conservation of DNA-Contact residues in DNA-binding Domains
Background: DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DN...
Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yun...
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
13 years 10 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BIOINFORMATICS
2008
97views more  BIOINFORMATICS 2008»
13 years 10 months ago
An integrated system for studying residue coevolution in proteins
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
Kevin Y. Yip, Prianka Patel, Philip M. Kim, Donald...
BMCBI
2010
155views more  BMCBI 2010»
13 years 10 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe