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BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
13 years 10 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 10 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 10 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2006
130views more  BMCBI 2006»
13 years 10 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
BMCBI
2006
45views more  BMCBI 2006»
13 years 10 months ago
A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB
Background: Sharing of microarray data within the research community has been greatly facilitated by the development of the disclosure and communication standards MIAME and MAGEML...
Tim F. Rayner, Philippe Rocca-Serra, Paul T. Spell...